Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1

C C Morton; R Taub; A Diamond; M A Lane; G M Cooper; P Leder

Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1

C C Morton
, R Taub
, A Diamond
, M A Lane
, G M Cooper
, P Leder

Division of Evolution, Infection and Genomics

Research output: Contribution to journal › Article › peer-review

Abstract

Blym-1, a transforming gene detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas, was mapped to the short arm of chromosome 1 (1p32) by chromosomal in situ hybridization. The Blym-1 gene was not physically linked to the cellular myc oncogene or to any of the immunoglobulin gene loci implicated in the characteristic chromosomal translocations in Burkitt lymphoma.

Original language	English
Pages (from-to)	173-5
Number of pages	3
Journal	Science
Volume	223
Issue number	4632
Publication status	Published - 13 Jan 1984

Keywords

Base Sequence
Burkitt Lymphoma
Chromosome Aberrations
Chromosome Mapping
Chromosomes, Human, 1-3
Genetic Linkage
Humans
Immunoglobulins
Male
Nucleic Acid Hybridization
Oncogenes
Translocation, Genetic
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1",

abstract = "Blym-1, a transforming gene detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas, was mapped to the short arm of chromosome 1 (1p32) by chromosomal in situ hybridization. The Blym-1 gene was not physically linked to the cellular myc oncogene or to any of the immunoglobulin gene loci implicated in the characteristic chromosomal translocations in Burkitt lymphoma.",

keywords = "Base Sequence, Burkitt Lymphoma, Chromosome Aberrations, Chromosome Mapping, Chromosomes, Human, 1-3, Genetic Linkage, Humans, Immunoglobulins, Male, Nucleic Acid Hybridization, Oncogenes, Translocation, Genetic, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.",

author = "Morton, \{C C\} and R Taub and A Diamond and Lane, \{M A\} and Cooper, \{G M\} and P Leder",

year = "1984",

month = jan,

day = "13",

language = "English",

volume = "223",

pages = "173--5",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science (A A A S)",

number = "4632",

}

TY - JOUR

T1 - Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1

AU - Morton, C C

AU - Taub, R

AU - Diamond, A

AU - Lane, M A

AU - Cooper, G M

AU - Leder, P

PY - 1984/1/13

Y1 - 1984/1/13

N2 - Blym-1, a transforming gene detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas, was mapped to the short arm of chromosome 1 (1p32) by chromosomal in situ hybridization. The Blym-1 gene was not physically linked to the cellular myc oncogene or to any of the immunoglobulin gene loci implicated in the characteristic chromosomal translocations in Burkitt lymphoma.

AB - Blym-1, a transforming gene detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas, was mapped to the short arm of chromosome 1 (1p32) by chromosomal in situ hybridization. The Blym-1 gene was not physically linked to the cellular myc oncogene or to any of the immunoglobulin gene loci implicated in the characteristic chromosomal translocations in Burkitt lymphoma.

KW - Base Sequence

KW - Burkitt Lymphoma

KW - Chromosome Aberrations

KW - Chromosome Mapping

KW - Chromosomes, Human, 1-3

KW - Genetic Linkage

KW - Humans

KW - Immunoglobulins

KW - Male

KW - Nucleic Acid Hybridization

KW - Oncogenes

KW - Translocation, Genetic

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Research Support, U.S. Gov't, P.H.S.

M3 - Article

C2 - 6691143

SN - 0036-8075

VL - 223

SP - 173

EP - 175

JO - Science

JF - Science

IS - 4632

ER -

Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1

Abstract

Keywords

UN SDGs

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