Mast cells in the synovium and synovial fluid in osteoarthritis

G. Dean; J. A. Hoyland; J. Denton; R. P. Donn; A. J. Freemont

Mast cells in the synovium and synovial fluid in osteoarthritis

G. Dean, J. A. Hoyland, J. Denton, R. P. Donn, A. J. Freemont

Research output: Contribution to journal › Article › peer-review

Abstract

SF and synovium from normal individuals and patients with OA, RA and traumatic arthritis (TA) were studied for the presence of mast cells (MC). When compared with normals, patients with OA had large numbers of intact and degranulated MC in the synovium and SF of diseased joints. The numbers of MC are comparable with those in RA where they have been implicated in the pathogenesis of joint damage. These data raise the possibility that in OA too MC may participate in the pathological processes in articular and periarticular tissues.

Original language	English
Pages (from-to)	671-675
Number of pages	4
Journal	British Journal of Rheumatology
Volume	32
Issue number	8
Publication status	Published - 1993

Keywords

Mast cells
Osteoarthritis

Cite this

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title = "Mast cells in the synovium and synovial fluid in osteoarthritis",

abstract = "SF and synovium from normal individuals and patients with OA, RA and traumatic arthritis (TA) were studied for the presence of mast cells (MC). When compared with normals, patients with OA had large numbers of intact and degranulated MC in the synovium and SF of diseased joints. The numbers of MC are comparable with those in RA where they have been implicated in the pathogenesis of joint damage. These data raise the possibility that in OA too MC may participate in the pathological processes in articular and periarticular tissues.",

keywords = "Mast cells, Osteoarthritis",

author = "G. Dean and Hoyland, {J. A.} and J. Denton and Donn, {R. P.} and Freemont, {A. J.}",

year = "1993",

language = "English",

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journal = "British Journal of Rheumatology",

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T1 - Mast cells in the synovium and synovial fluid in osteoarthritis

AU - Dean, G.

AU - Hoyland, J. A.

AU - Denton, J.

AU - Donn, R. P.

AU - Freemont, A. J.

PY - 1993

Y1 - 1993

N2 - SF and synovium from normal individuals and patients with OA, RA and traumatic arthritis (TA) were studied for the presence of mast cells (MC). When compared with normals, patients with OA had large numbers of intact and degranulated MC in the synovium and SF of diseased joints. The numbers of MC are comparable with those in RA where they have been implicated in the pathogenesis of joint damage. These data raise the possibility that in OA too MC may participate in the pathological processes in articular and periarticular tissues.

AB - SF and synovium from normal individuals and patients with OA, RA and traumatic arthritis (TA) were studied for the presence of mast cells (MC). When compared with normals, patients with OA had large numbers of intact and degranulated MC in the synovium and SF of diseased joints. The numbers of MC are comparable with those in RA where they have been implicated in the pathogenesis of joint damage. These data raise the possibility that in OA too MC may participate in the pathological processes in articular and periarticular tissues.

KW - Mast cells

KW - Osteoarthritis

M3 - Article

C2 - 8348268

SN - 1460-2172

VL - 32

SP - 671

EP - 675

JO - British Journal of Rheumatology

JF - British Journal of Rheumatology

IS - 8

ER -

Mast cells in the synovium and synovial fluid in osteoarthritis

Abstract

Keywords

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