Maternal malaria, birth size and blood pressure in nigerian newborns: Insights into the developmental origins of hypertension from the ibadan growth cohort

Omolola O. Ayoola, Isla Gemmell, Olayemi O. Omotade, Olusoji A. Adeyanju, J. Kennedy Cruickshank, Peter Ellis Clayton

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: Hypertension is an increasing health issue in sub-Saharan Africa where malaria remains common in pregnancy. We established a birth cohort in Nigeria to evaluate the early impact of maternal malaria on newborn blood pressure (BP). Methods: Anthropometric measurements, BP, blood films for malaria parasites and haematocrit were obtained in 436 mother-baby pairs. Women were grouped to distinguish between the timing of malaria parasitaemia as 'No Malaria', 'Malaria during pregnancy only' or 'Malaria at delivery', and parasite density as low (
    Original languageEnglish
    Article numbere24548
    JournalPLoS ONE
    Volume6
    Issue number9
    DOIs
    Publication statusPublished - 13 Sept 2011

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