Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay

S. R. Crosby; C. D. Anderton; M. Westwood; J. M P Holly; S. C. Cwyfan Hughes; M. Gibson; C. A. Morrison; R. J. Young; A. White

Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay

S. R. Crosby, C. D. Anderton, M. Westwood, J. M P Holly, S. C. Cwyfan Hughes, M. Gibson, C. A. Morrison, R. J. Young, A. White

Research output: Contribution to journal › Article › peer-review

Abstract

An immunoradiometric assay (IRMA) for the measurement of insulin-like growth factor-II (IGF-II) in human plasma has been developed, optimized and evaluated clinically in normal subjects and patients with disorders of the GH/IGF-I axis. Six monoclonal antibodies (MAbs) to recombinant human IGF-II (rhIGF-II) were produced, all of which had low cross-reactivity with rhIGF-I (

Original language	English
Pages (from-to)	141-150
Number of pages	9
Journal	Journal of Endocrinology
Volume	137
Issue number	1
Publication status	Published - 1993

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title = "Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay",

abstract = "An immunoradiometric assay (IRMA) for the measurement of insulin-like growth factor-II (IGF-II) in human plasma has been developed, optimized and evaluated clinically in normal subjects and patients with disorders of the GH/IGF-I axis. Six monoclonal antibodies (MAbs) to recombinant human IGF-II (rhIGF-II) were produced, all of which had low cross-reactivity with rhIGF-I (",

author = "Crosby, {S. R.} and Anderton, {C. D.} and M. Westwood and Holly, {J. M P} and {Cwyfan Hughes}, {S. C.} and M. Gibson and Morrison, {C. A.} and Young, {R. J.} and A. White",

year = "1993",

language = "English",

volume = "137",

pages = "141--150",

journal = "Journal of Endocrinology",

issn = "1479-6805",

publisher = "BioScientifica",

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TY - JOUR

T1 - Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay

AU - Crosby, S. R.

AU - Anderton, C. D.

AU - Westwood, M.

AU - Holly, J. M P

AU - Cwyfan Hughes, S. C.

AU - Gibson, M.

AU - Morrison, C. A.

AU - Young, R. J.

AU - White, A.

PY - 1993

Y1 - 1993

N2 - An immunoradiometric assay (IRMA) for the measurement of insulin-like growth factor-II (IGF-II) in human plasma has been developed, optimized and evaluated clinically in normal subjects and patients with disorders of the GH/IGF-I axis. Six monoclonal antibodies (MAbs) to recombinant human IGF-II (rhIGF-II) were produced, all of which had low cross-reactivity with rhIGF-I (

AB - An immunoradiometric assay (IRMA) for the measurement of insulin-like growth factor-II (IGF-II) in human plasma has been developed, optimized and evaluated clinically in normal subjects and patients with disorders of the GH/IGF-I axis. Six monoclonal antibodies (MAbs) to recombinant human IGF-II (rhIGF-II) were produced, all of which had low cross-reactivity with rhIGF-I (

M3 - Article

C2 - 8492071

SN - 1479-6805

VL - 137

SP - 141

EP - 150

JO - Journal of Endocrinology

JF - Journal of Endocrinology

IS - 1

ER -

Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay

Abstract

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