Measurement of renal blood flow by 131I-labelled sodium iodohippurate imaging in a rat model of herpes encephalitis

G M Cleator, P E Klapper, A G Lewis, H L Sharma, A M Smith

Research output: Contribution to journalArticlepeer-review

Abstract

Renal blood flow was assessed qualitatively over a 30 min period in a rat model of herpes encephalitis by extra-renal scintigraphic imaging following the injection of 131I-labelled sodium iodohippurate. No significant differences were observed for renal blood flow in either kidney between (or within) infected and control groups. Our data suggest that kidney function is not compromised in this animal model of encephalitis. The results are discussed in the context of the development of a non-invasive protocol for the in vivo diagnosis of herpes encephalitis.

Original languageEnglish
Pages (from-to)538-9
Number of pages2
JournalActa Radiologica
Volume31
Issue number5
Publication statusPublished - 1 Sept 1990

Keywords

  • Animals
  • Encephalitis/diagnostic imaging
  • Female
  • Herpesviridae Infections/diagnostic imaging
  • Iodine Radioisotopes
  • Iodohippuric Acid
  • Kidney/blood supply
  • Radionuclide Imaging
  • Rats
  • Rats, Inbred Strains

Fingerprint

Dive into the research topics of 'Measurement of renal blood flow by 131I-labelled sodium iodohippurate imaging in a rat model of herpes encephalitis'. Together they form a unique fingerprint.

Cite this