Measuring and using light in the melanopsin age

Robert J. Lucas; Stuart N. Peirson; David M. Berson; Timothy M. Brown; Howard M. Cooper; Charles A. Czeisler; Mariana G. Figueiro; Paul D. Gamlin; Steven W. Lockley; John B. O'Hagan; Luke L A Price; Ignacio Provencio; Debra J. Skene; George C. Brainard

doi:10.1016/j.tins.2013.10.004

Measuring and using light in the melanopsin age

Robert J. Lucas
, Stuart N. Peirson
, David M. Berson
, Timothy M. Brown
, Howard M. Cooper
, Charles A. Czeisler
, Mariana G. Figueiro
, Paul D. Gamlin
, Steven W. Lockley
, John B. O'Hagan
, Luke L A Price
, Ignacio Provencio
, Debra J. Skene
, George C. Brainard

Research output: Contribution to journal › Article › peer-review

Abstract

Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers. © 2013 Elsevier Ltd.

Original language	English
Pages (from-to)	1-9
Number of pages	8
Journal	Trends in neurosciences
Volume	37
Issue number	1
Early online date	25 Nov 2013
DOIs	https://doi.org/10.1016/j.tins.2013.10.004
Publication status	Published - Jan 2014

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10.1016/j.tins.2013.10.004

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Centre for Biological Timing
Lucas, R. (PI), Bechtold, D. (PI), Fustin, J.-M. (PI), Ashe, H. (PI), Brown, T. (PI), Blaikley, J. (PI), Brass, A. (PI), Chandola, T. (PI), Durrington, H. (PI), Else, K. (PI), Hepworth, M. (PI), Hunter, L. (PI), Kadler, K. (PI), Kitchen, G. (PI), Loudon, A. (PI), Macdonald, A. (PI), Mcbeth, J. (PI), Milosavljevic, N. (PI), Rattray, M. (PI), Rutter, M. (PI), Sharrocks, A. (PI), Spiller, D. (PI), Storchi, R. (PI), Belle, M. (PI), Meng, Q.-J. (PI), Allen, A. (PI), Dixon, W. (PI), Gibbs, J. (PI), Hazel, A. (PI), Papalopulu, N. (PI), Ray, D. (PI), White, M. (PI), Chang, J. (PI), Bano Otalora, B. (CoI), Zavala, E. (PI), Orlowska-Feuer, P. (PI) & Didikoglu, A. (PI)
Project: Research
Adaption and Rhythmicity in the Contribution of Cones to Irradiance Coding in Circadian and Non Image Forming Pathways
Lucas, R. (PI) & Piggins, H. (CoI)
1/11/07 → 31/10/10
Project: Research

A new international lighting standard that meets our biological needs
Lucas, R. (Participant), Brown, T. (Participant), Allen, A. (Participant) & Bailes, H. (Participant)
Impact: Technological impacts, Health and wellbeing, Society and culture, Economic
A new international measurement standard and guidelines for healthy lighting
Brown, T. (Participant), Lucas, R. (Participant) & Allen, A. (Participant)
Impact: Society and culture, Policy, Economic, Awareness and understanding, Health and wellbeing

Cite this

@article{50fb17aff4f045d88e155710556510e3,

title = "Measuring and using light in the melanopsin age",

abstract = "Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers. {\textcopyright} 2013 Elsevier Ltd.",

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doi = "10.1016/j.tins.2013.10.004",

language = "English",

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AU - Lucas, Robert J.

AU - Peirson, Stuart N.

AU - Berson, David M.

AU - Brown, Timothy M.

AU - Cooper, Howard M.

AU - Czeisler, Charles A.

AU - Figueiro, Mariana G.

AU - Gamlin, Paul D.

AU - Lockley, Steven W.

AU - O'Hagan, John B.

AU - Price, Luke L A

AU - Provencio, Ignacio

AU - Skene, Debra J.

AU - Brainard, George C.

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N2 - Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers. © 2013 Elsevier Ltd.

AB - Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers. © 2013 Elsevier Ltd.

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Measuring and using light in the melanopsin age

Abstract

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Projects

Centre for Biological Timing

Adaption and Rhythmicity in the Contribution of Cones to Irradiance Coding in Circadian and Non Image Forming Pathways

Impacts

A new international lighting standard that meets our biological needs

A new international measurement standard and guidelines for healthy lighting

Cite this