Abstract
Endogenous vitamin D deficiency (low serum 25(OH)D3) is a necessary but insufficient requirement for the genesis of vitamin D-deficiency rickets and osteomalacia. The magnitude of the independent contributions of dietary factors to rachitic and osteomalacic risk remains uncertain. We reanalysed two weighed dietary surveys of sixty-two cases of rickets and osteomalacia and 113 normal women and children. The independent associations of four dietary variables (vitamin D, Ca, fibre and meat intakes) and daylight outdoor exposure with rachitic and osteomalacic relative risk were estimated by multivariate logistic regression. Meat and fibre intakes showed significant negative and positive associations respectively with rachitic and osteomalacic relative risk (RR; zero meat intake: RR 29.8 (95 % CI 4.96, 181), P
Original language | English |
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Pages (from-to) | 983-991 |
Number of pages | 8 |
Journal | British Journal of Nutrition |
Volume | 94 |
Issue number | 6 |
Publication status | Published - Dec 2005 |
Keywords
- Asian rickets
- Nutritional rickets
- Osteomalacic risk factors
- Rachitic risk factors