Mechanisms of improved survival from intensive followup in colorectal cancer: A hypothesis

A. G. Renehan; M. Egger; M. P. Saunders; S. T. O'Dwyer

doi:10.1038/sj.bjc.6602369

Mechanisms of improved survival from intensive followup in colorectal cancer: A hypothesis

A. G. Renehan, M. Egger, M. P. Saunders, S. T. O'Dwyer

Research output: Contribution to journal › Article › peer-review

Abstract

A meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)- however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions. © 2005 Cancer Research UK.

Original language	English
Pages (from-to)	430-433
Number of pages	3
Journal	British Journal of Cancer
Volume	92
Issue number	3
DOIs	https://doi.org/10.1038/sj.bjc.6602369
Publication status	Published - 14 Feb 2005

Keywords

Colorectal cancer
Followup
Meta-analysis
Recurrences
Salvage surgery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.bjc.6602369

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title = "Mechanisms of improved survival from intensive followup in colorectal cancer: A hypothesis",

abstract = "A meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)- however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions. {\textcopyright} 2005 Cancer Research UK.",

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AU - Renehan, A. G.

AU - Egger, M.

AU - Saunders, M. P.

AU - O'Dwyer, S. T.

PY - 2005/2/14

Y1 - 2005/2/14

N2 - A meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)- however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions. © 2005 Cancer Research UK.

AB - A meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)- however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions. © 2005 Cancer Research UK.

KW - Colorectal cancer

KW - Followup

KW - Meta-analysis

KW - Recurrences

KW - Salvage surgery

U2 - 10.1038/sj.bjc.6602369

DO - 10.1038/sj.bjc.6602369

M3 - Article

SN - 0007-0920

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SP - 430

EP - 433

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 3

ER -

Mechanisms of improved survival from intensive followup in colorectal cancer: A hypothesis

Abstract

Keywords

UN SDGs

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