Membrane trafficking in health and disease

Rebecca Yarwood; John Hellicar; Philip G. Woodman; Martin Lowe

doi:10.1242/dmm.043448

Membrane trafficking in health and disease

Rebecca Yarwood, John Hellicar, Philip G. Woodman, Martin Lowe

Research output: Contribution to journal › Article › peer-review

Abstract

Membrane trafficking pathways are essential for the viability and growth of cells, and play a major role in the interaction of cells with their environment. In this At a Glance article and accompanying poster, we outline the major cellular trafficking pathways and discuss how defects in the function of the molecular machinery that mediates this transport lead to various diseases in humans. We also briefly discuss possible therapeutic approaches that may be used in the future treatment of trafficking-based disorders.

Original language	Undefined
Journal	Disease Models & Mechanisms
DOIs	https://doi.org/10.1242/dmm.043448
Publication status	Published - 30 Apr 2020

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10.1242/dmm.043448

Cite this

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title = "Membrane trafficking in health and disease",

abstract = "Membrane trafficking pathways are essential for the viability and growth of cells, and play a major role in the interaction of cells with their environment. In this At a Glance article and accompanying poster, we outline the major cellular trafficking pathways and discuss how defects in the function of the molecular machinery that mediates this transport lead to various diseases in humans. We also briefly discuss possible therapeutic approaches that may be used in the future treatment of trafficking-based disorders.",

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AB - Membrane trafficking pathways are essential for the viability and growth of cells, and play a major role in the interaction of cells with their environment. In this At a Glance article and accompanying poster, we outline the major cellular trafficking pathways and discuss how defects in the function of the molecular machinery that mediates this transport lead to various diseases in humans. We also briefly discuss possible therapeutic approaches that may be used in the future treatment of trafficking-based disorders.

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