Metabolic Models

Jean-Marc Schwartz; Zita Soons

doi:10.1016/B978-0-323-95502-7.00025-7

Metabolic Models

Jean-Marc Schwartz, Zita Soons

Division of Evolution, Infection and Genomics

University Hospital Aachen

Research output: Chapter in Book/Conference proceeding › Entry for encyclopedia/dictionary › peer-review

Abstract

Metabolic networks are generally better known than other types of cellular networks, and they are therefore well suited for the development of computational models. A range of different techniques can be used to model systems of metabolic reactions, from kinetic methods which seek to represent the exact dynamics of fluxes over time, to constraint-based and structural methods which only consider steady state situations. Altogether these methods have led to important progress in our understanding of cellular functions and how they are regulated by exchanges with the extracellular environment.

Original language	English
Title of host publication	Encyclopedia of Bioinformatics and Computational Biology
Editors	Shoba Ranganathan, Mario Cannataro, Mohammad Asif Khan
Publisher	Elsevier BV
Pages	510-518
Number of pages	8
Volume	3
Edition	2
ISBN (Electronic)	9780323955034
ISBN (Print)	9780323955027
DOIs	https://doi.org/10.1016/B978-0-323-95502-7.00025-7
Publication status	Published - 22 Mar 2025

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10.1016/B978-0-323-95502-7.00025-7

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AB - Metabolic networks are generally better known than other types of cellular networks, and they are therefore well suited for the development of computational models. A range of different techniques can be used to model systems of metabolic reactions, from kinetic methods which seek to represent the exact dynamics of fluxes over time, to constraint-based and structural methods which only consider steady state situations. Altogether these methods have led to important progress in our understanding of cellular functions and how they are regulated by exchanges with the extracellular environment.

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DO - 10.1016/B978-0-323-95502-7.00025-7

M3 - Entry for encyclopedia/dictionary

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SP - 510

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BT - Encyclopedia of Bioinformatics and Computational Biology

A2 - Ranganathan, Shoba

A2 - Cannataro, Mario

A2 - Khan, Mohammad Asif

PB - Elsevier BV

ER -

Metabolic Models

Abstract

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