Metabolomic systems biology of trypanosomes

Michael P. Barrett; Barbara M. Bakker; Rainer Breitling

doi:10.1017/S003118201000017X

Metabolomic systems biology of trypanosomes

Michael P. Barrett, Barbara M. Bakker, Rainer Breitling

Research output: Contribution to journal › Article › peer-review

Abstract

Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental perturbation, and to identify the targets of drugs. Here we discuss recent developments in metabolomic analysis, from the perspective of trypanosome research, highlighting remaining challenges and the most promising areas for future research. Copyright © 2010 Cambridge University Press.

Original language	English
Pages (from-to)	1285-1290
Number of pages	5
Journal	Parasitology
Volume	137
Issue number	9
DOIs	https://doi.org/10.1017/S003118201000017X
Publication status	Published - Aug 2010

Keywords

ab initio networks
mass spectrometry
Metabolomics
Orbitrap
Trypanosoma brucei

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1017/S003118201000017X

Cite this

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title = "Metabolomic systems biology of trypanosomes",

abstract = "Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental perturbation, and to identify the targets of drugs. Here we discuss recent developments in metabolomic analysis, from the perspective of trypanosome research, highlighting remaining challenges and the most promising areas for future research. Copyright {\textcopyright} 2010 Cambridge University Press.",

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AU - Bakker, Barbara M.

AU - Breitling, Rainer

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AB - Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental perturbation, and to identify the targets of drugs. Here we discuss recent developments in metabolomic analysis, from the perspective of trypanosome research, highlighting remaining challenges and the most promising areas for future research. Copyright © 2010 Cambridge University Press.

KW - ab initio networks

KW - mass spectrometry

KW - Metabolomics

KW - Orbitrap

KW - Trypanosoma brucei

U2 - 10.1017/S003118201000017X

DO - 10.1017/S003118201000017X

M3 - Article

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SP - 1285

EP - 1290

JO - Parasitology

JF - Parasitology

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ER -

Metabolomic systems biology of trypanosomes

Abstract

Keywords

UN SDGs

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