Metacognitive Therapy in Major Depression: An Open Trial of Comorbid Cases

Odin Hjemdal, Roger Hagen, Stian Solem, Henrik Nordahl, Leif Edward Ottesen Kennair, Truls Ryum, Hans M. Nordahl, Adrian Wells

Research output: Contribution to journalArticlepeer-review


This open trial investigated the transdiagnostic effects of metacognitive therapy (MCT) in patients with severe major depressive disorder and comorbid psychiatric disorder. Ten patients were treated with MCT over 10 sessions and were assessed with measures of depression, anxiety, rumination, and metacognitions at pre- and posttreatment and at 6 months follow-up. None of the patients were diagnosed as depressed at posttreatment, and of the initial 21 total diagnoses at pretreatment only 3 diagnoses remained at postintervention. The effect sizes were large for symptoms of depression, rumination, and worry. At 6 months follow-up standardized recovery criteria on the BDI showed that 70% were recovered, 20% improved, and 10% unchanged. The results indicate that MCT was associated with high rates of transdiagnostic improvement.

Original languageEnglish
Pages (from-to)312-318
Number of pages7
JournalCognitive and Behavioral Practice
Issue number3
Early online date26 Jul 2016
Publication statusPublished - 1 Aug 2017


  • anxiety
  • comorbidity
  • depression
  • metacognitive therapy
  • rumination


Dive into the research topics of 'Metacognitive Therapy in Major Depression: An Open Trial of Comorbid Cases'. Together they form a unique fingerprint.

Cite this