Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?

Maria Peiris-Pagès; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti

doi:10.1016/j.cmet.2015.11.008

Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?

Maria Peiris-Pagès, Ubaldo E Martinez-Outschoorn, Federica Sotgia, Michael P Lisanti

Research output: Contribution to journal › Article › peer-review

Abstract

The role of reactive oxygen species (ROS) and antioxidants in cancer is controversial because of their context-dependent ability to promote or suppress tumorigenesis. Piskounova et al. (2015) now show that ROS limit distant metastasis: only cells with increased antioxidant capacity are able to succeed in their purpose to metastasize.

Original language	English
Journal	Cell Metabolism
Volume	22
Issue number	6
DOIs	https://doi.org/10.1016/j.cmet.2015.11.008
Publication status	Published - 1 Dec 2015

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10.1016/j.cmet.2015.11.008

Cite this

@article{4c2c523a88de49a386f2b650871b734c,

title = "Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?",

abstract = "The role of reactive oxygen species (ROS) and antioxidants in cancer is controversial because of their context-dependent ability to promote or suppress tumorigenesis. Piskounova et al. (2015) now show that ROS limit distant metastasis: only cells with increased antioxidant capacity are able to succeed in their purpose to metastasize.",

author = "Maria Peiris-Pag{\`e}s and Martinez-Outschoorn, {Ubaldo E} and Federica Sotgia and Lisanti, {Michael P}",

year = "2015",

month = dec,

day = "1",

doi = "10.1016/j.cmet.2015.11.008",

language = "English",

volume = "22",

journal = "Cell Metabolism",

issn = "1550-4131",