Abstract
A method for monitoring reactions or chemical processes, such as solid phase synthesis, comprises detecting chromaphoric changes using attenuated total reflectance spectroscopy (ATR) techniques, preferably in the UV/ visible waveband, e.g. 150 to 550 nm. The spectral data is collected and analysed using multi-variant data manipulation processes such as principal component analysis. The collection and analysis may be performed in real time.
| Original language | English |
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| Patent number | GB2358921 |
| Publication status | Published - 8 Aug 2001 |