Method validation of circulating tumour cell enumeration at low cell counts

Jeffrey Cummings, Karen Morris, Cong Zhou, Robert Sloane, Matt Lancashire, Daniel Morris, Stephen Bramley, Matt Krebs, Leila Khoja, Caroline Dive

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: Circulating tumour cells (CTC) are receiving increasing attention as prognostic, predictive and pharmacodynamic biomarkers in cancer patients. However, their clinical significance can be dependent on an accurate determination of CTC around cut-off values at low cell counts (
    Original languageEnglish
    Article number415
    Pages (from-to)415
    JournalBMC Cancer
    Volume13
    Issue number13
    DOIs
    Publication statusPublished - 11 Sep 2013

    Keywords

    • Circulating tumour cells
    • Enumeration
    • Low cell counts
    • Method validation
    • Predictive biomarker
    • Statistical analysis

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