Molecular motors and the Golgi complex: Staying put and moving through

Kim Brownhill, Laura Wood, Viki Allan

    Research output: Contribution to journalArticlepeer-review


    The Golgi apparatus is a highly dynamic organelle through which nascent proteins released from the endoplasmic reticulum (ER) are trafficked. Proteins are post-translationally modified within the Golgi and subsequently packaged into carriers for transport to a variety of cellular destinations. This transit of proteins, as well as the maintenance of Golgi structure and position, is highly dependent upon the actin and microtubule cytoskeletons and their associated molecular motors. Here we review how motors contribute to the correct functioning of the Golgi in higher eukaryotes and discuss the secretory pathway as a model system for studying cooperation between motor proteins. © 2009 Elsevier Ltd. All rights reserved.
    Original languageEnglish
    Pages (from-to)784-792
    Number of pages8
    JournalSeminars in Cell and Developmental Biology
    Issue number7
    Publication statusPublished - Sept 2009


    • Actin
    • Cell migration
    • Dynein
    • Golgi
    • Kinesin
    • Microtubule
    • Myosin
    • Secretion


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