Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

Marianna Yaneze Arteta; Debora Berti; Costanza Montis; Richard A. Campbell; Luke A. Clifton; Maximilian W.A. Skoda; Olaf Soltwedel; Piero Baglioni; Tommy Nylander

doi:10.1039/c4sm01733a

Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

Marianna Yaneze Arteta, Debora Berti, Costanza Montis, Richard A. Campbell, Luke A. Clifton, Maximilian W.A. Skoda, Olaf Soltwedel, Piero Baglioni^*, Tommy Nylander

^*Corresponding author for this work

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Abstract

We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids. This journal is

Original language	English
Pages (from-to)	8401-8405
Number of pages	5
Journal	Soft Matter
Volume	10
Issue number	42
DOIs	https://doi.org/10.1039/c4sm01733a
Publication status	Published - 14 Nov 2014

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abstract = "We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids. This journal is",

author = "Arteta, {Marianna Yaneze} and Debora Berti and Costanza Montis and Campbell, {Richard A.} and Clifton, {Luke A.} and Skoda, {Maximilian W.A.} and Olaf Soltwedel and Piero Baglioni and Tommy Nylander",

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AU - Arteta, Marianna Yaneze

AU - Berti, Debora

AU - Montis, Costanza

AU - Campbell, Richard A.

AU - Clifton, Luke A.

AU - Skoda, Maximilian W.A.

AU - Soltwedel, Olaf

AU - Baglioni, Piero

AU - Nylander, Tommy

PY - 2014/11/14

Y1 - 2014/11/14

N2 - We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids. This journal is

AB - We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids. This journal is

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DO - 10.1039/c4sm01733a

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AN - SCOPUS:84924043635

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JF - Soft Matter

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ER -

Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

Abstract

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