Molecular Trefoil Knot from a Trimeric Circular Helicate

Liang Zhang; David August; Jiankang Zhong; George Whitehead; Inigo Vitorica-Yrezabal; David Leigh

doi:10.1021/jacs.8b00738

Molecular Trefoil Knot from a Trimeric Circular Helicate

Liang Zhang, David August, Jiankang Zhong, George Whitehead, Inigo Vitorica-Yrezabal, David Leigh

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Abstract

We report the two-step synthesis of a molecular trefoil knot in 90 % overall yield through the self-assembly of a twelve-component trimeric circular zinc helicate followed by ring closing metathesis of six pendant alkene chains. Both the trimeric circular helicate intermediate and the resulting trefoil knot were characterized by NMR spectroscopy, mass spectrometry and X-ray crystallography.

Original language	English
Pages (from-to)	4982-4985
Number of pages	4
Journal	American Chemical Society. Journal
Volume	140
Issue number	15
Early online date	14 Mar 2018
DOIs	https://doi.org/10.1021/jacs.8b00738
Publication status	Published - 18 Apr 2018

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10.1021/jacs.8b00738

Rvsd2Mar2018 MolTrefoilKnotTrimericCircHelicate JACSAccepted author manuscript, 1.12 MB

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title = "Molecular Trefoil Knot from a Trimeric Circular Helicate",

abstract = "We report the two-step synthesis of a molecular trefoil knot in 90 % overall yield through the self-assembly of a twelve-component trimeric circular zinc helicate followed by ring closing metathesis of six pendant alkene chains. Both the trimeric circular helicate intermediate and the resulting trefoil knot were characterized by NMR spectroscopy, mass spectrometry and X-ray crystallography.",

author = "Liang Zhang and David August and Jiankang Zhong and George Whitehead and Inigo Vitorica-Yrezabal and David Leigh",

note = "Funding Information: We thank Dr. Jonathan D. Danon for the preparation of compound 1 and Dr. Jean-Franc{\c o} is Lemonnier and Dr. Javier Jaramillo-Garcia for useful discussions. This work was supported by the Engineering and Physical Sciences Research Council (EPSRC). We are grateful for a President{\textquoteright}s Doctoral Scholarship (to L.Z.) and the China Scholarship Council for a studentship (to J.Z.). D.A.L. is a Royal Society Research Professor. Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",

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doi = "10.1021/jacs.8b00738",

language = "English",

volume = "140",

pages = "4982--4985",

journal = "American Chemical Society. Journal ",

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T1 - Molecular Trefoil Knot from a Trimeric Circular Helicate

AU - Zhang, Liang

AU - August, David

AU - Zhong, Jiankang

AU - Whitehead, George

AU - Vitorica-Yrezabal, Inigo

AU - Leigh, David

N1 - Funding Information: We thank Dr. Jonathan D. Danon for the preparation of compound 1 and Dr. Jean-Franco̧ is Lemonnier and Dr. Javier Jaramillo-Garcia for useful discussions. This work was supported by the Engineering and Physical Sciences Research Council (EPSRC). We are grateful for a President’s Doctoral Scholarship (to L.Z.) and the China Scholarship Council for a studentship (to J.Z.). D.A.L. is a Royal Society Research Professor. Publisher Copyright: © 2018 American Chemical Society.

PY - 2018/4/18

Y1 - 2018/4/18

N2 - We report the two-step synthesis of a molecular trefoil knot in 90 % overall yield through the self-assembly of a twelve-component trimeric circular zinc helicate followed by ring closing metathesis of six pendant alkene chains. Both the trimeric circular helicate intermediate and the resulting trefoil knot were characterized by NMR spectroscopy, mass spectrometry and X-ray crystallography.

AB - We report the two-step synthesis of a molecular trefoil knot in 90 % overall yield through the self-assembly of a twelve-component trimeric circular zinc helicate followed by ring closing metathesis of six pendant alkene chains. Both the trimeric circular helicate intermediate and the resulting trefoil knot were characterized by NMR spectroscopy, mass spectrometry and X-ray crystallography.

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UR - http://www.mendeley.com/research/molecular-trefoil-knot-trimeric-circular-helicate

U2 - 10.1021/jacs.8b00738

DO - 10.1021/jacs.8b00738

M3 - Article

SN - 0002-7863

VL - 140

SP - 4982

EP - 4985

JO - American Chemical Society. Journal

JF - American Chemical Society. Journal

IS - 15

ER -

Molecular Trefoil Knot from a Trimeric Circular Helicate

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CCDC 1815059: Experimental Crystal Structure Determination

CCDC 1815058: Experimental Crystal Structure Determination

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Molecular Trefoil Knot from a Trimeric Circular Helicate

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CCDC 1815059: Experimental Crystal Structure Determination

CCDC 1815058: Experimental Crystal Structure Determination

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