Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Xiaotong Feng; Jon Ashley; Tongchang Zhou; Arnab Halder; Yi Sun

doi:10.1039/c8an00711j

Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Xiaotong Feng, Jon Ashley, Tongchang Zhou, Arnab Halder, Yi Sun

Pharmacy

Research output: Contribution to journal › Article › peer-review

Abstract

Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

Original language	English
Pages (from-to)	2750-2754
Number of pages	5
Journal	Analyst
Volume	143
Issue number	12
Early online date	16 May 2018
DOIs	https://doi.org/10.1039/c8an00711j
Publication status	Published - 2018

Access to Document

10.1039/c8an00711j

Cite this

@article{36cfef115e89438988ff539180f185d4,

title = "Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction",

abstract = "Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.",

author = "Xiaotong Feng and Jon Ashley and Tongchang Zhou and Arnab Halder and Yi Sun",

year = "2018",

doi = "10.1039/c8an00711j",

language = "English",

volume = "143",

pages = "2750--2754",

journal = "Analyst",

issn = "0003-2654",

publisher = "Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

AU - Feng, Xiaotong

AU - Ashley, Jon

AU - Zhou, Tongchang

AU - Halder, Arnab

AU - Sun, Yi

PY - 2018

Y1 - 2018

N2 - Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

AB - Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

U2 - 10.1039/c8an00711j

DO - 10.1039/c8an00711j

M3 - Article

SN - 0003-2654

VL - 143

SP - 2750

EP - 2754

JO - Analyst

JF - Analyst

IS - 12

ER -

Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Abstract

Access to Document

Fingerprint

Cite this