Motoring around the Golgi

Victoria J. Allan, Heather M. Thompson, Mark A. McNiven

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The Golgi apparatus is a dynamic organelle through which nascent secretory and transmembrane proteins are transported, post-translationally modified and finally packaged into carrier vesicles for transport along the cytoskeleton to a variety of destinations. In the past decade, studies have shown that a number of 'molecular motors' are involved in maintaining the proper structure and function of the Golgi apparatus. Here, we review just some of the many functions performed by these mechanochemical enzymes - dyneins, kinesins, myosins and dynamin - in relation to the Golgi apparatus.
    Original languageEnglish
    Pages (from-to)E236-E242
    JournalNature Cell Biology
    Volume4
    Issue number10
    DOIs
    Publication statusPublished - 1 Oct 2002

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