Mucins in prostatic carcinoma

S. E. Pinder; Raymond Mcmahon

doi:10.1111/J.1365-2559.1990.TB01058.X

Mucins in prostatic carcinoma

Research output: Contribution to journal › Article › peer-review

Abstract

Mucin production by prostatic carcinomas is not unusual and the identification of acidic mucin with an appropriate stain may be a useful adjunct in routine diagnostic surgical pathology. In our series of 53 cases of prostatic carcinoma, 20 (38%) showed significant acidic mucin production. This may allow differentiation from benign, hyperplastic tissues which produce neutral mucins only. A case of colloid carcinoma of prostate is described which satisfies Elbadawi's criteria for this uncommon variant. Some suggestions are made which, if rigorously applied, will permit the recognition of genuine cases of colloid carcinoma and of the prognostic significance of mucin-rich tumours.

Original language	English
Pages (from-to)	43-46
Number of pages	3
Journal	Histopathology
Volume	16
Issue number	1
DOIs	https://doi.org/10.1111/J.1365-2559.1990.TB01058.X
Publication status	Published - 1990

Keywords

Mucinous carcinoma
Mucins
Prostate
Prostatic neoplasms

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/J.1365-2559.1990.TB01058.X

Cite this

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title = "Mucins in prostatic carcinoma",

abstract = "Mucin production by prostatic carcinomas is not unusual and the identification of acidic mucin with an appropriate stain may be a useful adjunct in routine diagnostic surgical pathology. In our series of 53 cases of prostatic carcinoma, 20 (38%) showed significant acidic mucin production. This may allow differentiation from benign, hyperplastic tissues which produce neutral mucins only. A case of colloid carcinoma of prostate is described which satisfies Elbadawi's criteria for this uncommon variant. Some suggestions are made which, if rigorously applied, will permit the recognition of genuine cases of colloid carcinoma and of the prognostic significance of mucin-rich tumours.",

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AU - Pinder, S. E.

AU - Mcmahon, Raymond

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N2 - Mucin production by prostatic carcinomas is not unusual and the identification of acidic mucin with an appropriate stain may be a useful adjunct in routine diagnostic surgical pathology. In our series of 53 cases of prostatic carcinoma, 20 (38%) showed significant acidic mucin production. This may allow differentiation from benign, hyperplastic tissues which produce neutral mucins only. A case of colloid carcinoma of prostate is described which satisfies Elbadawi's criteria for this uncommon variant. Some suggestions are made which, if rigorously applied, will permit the recognition of genuine cases of colloid carcinoma and of the prognostic significance of mucin-rich tumours.

AB - Mucin production by prostatic carcinomas is not unusual and the identification of acidic mucin with an appropriate stain may be a useful adjunct in routine diagnostic surgical pathology. In our series of 53 cases of prostatic carcinoma, 20 (38%) showed significant acidic mucin production. This may allow differentiation from benign, hyperplastic tissues which produce neutral mucins only. A case of colloid carcinoma of prostate is described which satisfies Elbadawi's criteria for this uncommon variant. Some suggestions are made which, if rigorously applied, will permit the recognition of genuine cases of colloid carcinoma and of the prognostic significance of mucin-rich tumours.

KW - Mucinous carcinoma

KW - Mucins

KW - Prostate

KW - Prostatic neoplasms

UR - https://publons.com/wos-op/publon/61091795/

U2 - 10.1111/J.1365-2559.1990.TB01058.X

DO - 10.1111/J.1365-2559.1990.TB01058.X

M3 - Article

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SN - 0309-0167

VL - 16

SP - 43

EP - 46

JO - Histopathology

JF - Histopathology

IS - 1

ER -

Mucins in prostatic carcinoma

Abstract

Keywords

UN SDGs

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