TY - JOUR
T1 - Multidimensional indices in the assessment of chronic obstructive pulmonary disease
AU - Corlateanu, Alexandru
AU - Plahotniuc, Alexandra
AU - Corlateanu, Olga
AU - Botnaru, Victor
AU - Bikov, Andras
AU - Mathioudakis, Alexander G.
AU - Covantev, Serghei
AU - Siafakas, Nikolaos
PY - 2021/8/1
Y1 - 2021/8/1
N2 - Chronic obstructive pulmonary disease (COPD), a very common disease, is the third leading cause of death worldwide. Due to the significant heterogeneity of clinical phenotypes of COPD there is no single method suitable for predicting patients’ health status and outcomes, and therefore multidimensional indices, assessing different components of the disease, were developed and are recommended for clinical practice by international guidelines. Several indices have been widely accepted: BODE and its modifications, ADO, DOSE, CODEX, COTE. They differ in their composition and aim, while they are more accurate and better validated in specific settings and populations. We review the characteristics, strengths and limitations of these indices, and we discuss their role in routine management of patients with COPD, as well as in specific clinical scenarios, such as resuscitation and ceiling of care, or decisions to offer more invasive treatments. This analysis may help clinicians to use those indexes in a more practical and appropriate way.
AB - Chronic obstructive pulmonary disease (COPD), a very common disease, is the third leading cause of death worldwide. Due to the significant heterogeneity of clinical phenotypes of COPD there is no single method suitable for predicting patients’ health status and outcomes, and therefore multidimensional indices, assessing different components of the disease, were developed and are recommended for clinical practice by international guidelines. Several indices have been widely accepted: BODE and its modifications, ADO, DOSE, CODEX, COTE. They differ in their composition and aim, while they are more accurate and better validated in specific settings and populations. We review the characteristics, strengths and limitations of these indices, and we discuss their role in routine management of patients with COPD, as well as in specific clinical scenarios, such as resuscitation and ceiling of care, or decisions to offer more invasive treatments. This analysis may help clinicians to use those indexes in a more practical and appropriate way.
U2 - 10.1016/j.rmed.2021.106519
DO - 10.1016/j.rmed.2021.106519
M3 - Article
SN - 0954-6111
VL - 185
JO - Respiratory Medicine
JF - Respiratory Medicine
M1 - 106519
ER -