Molecular motors are a fascinating group of proteins that have vital roles in a huge variety of cellular processes. They all share the ability to produce force through the hydrolysis of adenosine triphosphate, and fall into classes groups: the kinesins, myosins and the dyneins. The kinesin superfamily itself can be split into three major groups depending on the position of the motor domain, which is localized N-terminally, C-terminally, or internally. This review focuses on the N-terminal kinesins, providing a brief overview of their roles within the cell, and illustrating recent key developments in our understanding of how these proteins function. Copyright © Blackwell Munksgaard 2004.
|Number of pages||10|
|Journal||Traffic (Malden): the international journal of intracellular transport|
|Publication status||Published - Jun 2004|
- Cargo binding
- Transport of N-terminal kinesins