Nanocomposite Hydrogels: 3D Polymer-Nanoparticle Synergies for On-Demand Drug Delivery.

Sonia Merino, Cristina Martín, Kostas Kostarelos, Maurizio Prato, Ester Vázquez

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for obtaining multicomponent systems with diverse functionality within a hybrid hydrogel network. Nanoparticle-hydrogel combinations add synergistic benefits to the new 3D structures. Nanogels as carriers for cancer therapy and injectable gels with improved self-healing properties have also been described as new nanocomposite systems.
    Original languageEnglish
    JournalACS Nano
    Volume9
    Issue number5
    DOIs
    Publication statusPublished - 26 May 2015

    Keywords

    • external field
    • hydrogel
    • nanocomposite
    • nanogel
    • nanoparticle
    • on-demand delivery
    • self-healing
    • stimuli-response

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