Nanoparticles for highly efficient multiphoton fluorescence bioimaging

Laura Martinez Maestro, Emma Martin Rodriguez, Fiorenzo Vetrone, Rafik Naccache, Hector Loro Ramirez, Daniel Jaque, John A. Capobianco, Jose Garcia Sole

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In this paper, we demonstrate for the first time that the new class of fluoride-based inorganic upconverting nanoparticles, NaYF4:Er3+, Yb3+, are the most efficient multiphoton excited fluorescent nanoparticles developed to date. The near-infrared-to-visible conversion efficiency of the aforementioned nanoparticles surpasses that of CdSe quantum dots and gold nanorods, which are the commercially available inorganic fluorescent nanoprobes presently used for multiphoton fluorescence bioimaging. The results presented here open new perspectives for the implementation of fluorescence tomography by multiphoton fluorescence imaging.
    Original languageEnglish
    Pages (from-to)23544-23553
    JournalOptics Express
    Volume18
    Issue number23
    DOIs
    Publication statusPublished - 8 Nov 2010

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