Abstract
(2S)-4-amino-2-hydroxybutyrate (AHBA) is a side chain that is important for the antibiotic activities of amino-glycosides. The elucidation of the biosynthetic pathway to AHBA, by Spencer et al. in this issue of Chemistry & Biology [1], reveals several surprises and will facilitate biosynthetic engineering of new improved aminoglycoside antibiotics. ©2005 Elsevier Ltd All rights reserved.
Original language | English |
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Pages (from-to) | 611-613 |
Number of pages | 2 |
Journal | Chemistry and Biology |
Volume | 12 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2005 |