Neurodevelopmental status at 1 year predicts neuropsychiatric outcome at 14-15 years of age in very preterm infants

S. Roth, J. Wyatt, J. Baudin, J. Townsend, L. Rifkin, T. Rushe, C. Amiel-Tison, A. L. Stewart

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: Neurodevelopmental and behavioural problems have been repeatedly reported in very preterm survivors, often showing themselves later in childhood as poor school performance. Early identification of problems would mean that appropriate remedial therapy can be implemented. We have previously shown that neurodevelopmental status at 1 year was predictive of outcome at 8 years in a cohort of preterm infants. The aim of this paper was to see if neurodevelopmental outcome in adolescence could be predicted by assessment by 1 year in the same cohort of pretem infants. Study design: Prospective cohort study. Subjects: 150 adolescents, born before 33 weeks gestation. Outcome measures: Neurological examination, developmental quotient, vision and hearing by 1 year. At 14-15 years, neurological examination, school performance questionnaire, Schonnell test of reading age, a premorbid adjustment score, Rutter behavioural score and for those born from 1981, cognitive tests (WISC-R). Results: A highly significant relationship existed between neurological status by 1 year and the need for extra educational provision, overall neurodevelopmental status, cognitive function in those that had their IQs measured and premorbid adjustment score of prepsychotic symptoms in adolescence. However, status at 1 year was not predictive of adolescent reading age or behavioural score. Conclusions: Neurodevelopmental assessment at 1 year is predictive of school performance and outcome in the adolescent period. © 2001 Elsevier Science Ireland Ltd. All rights reserved.
    Original languageEnglish
    Pages (from-to)81-89
    Number of pages8
    JournalEarly Human Development
    Volume65
    Issue number2
    DOIs
    Publication statusPublished - 2001

    Keywords

    • Neurodevelopmental status
    • Neuropsychiatric outcome
    • Preterm infants

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