Neuroglia in Neurodegenerative Diseases

Alexei Verkhratsky (Editor), Margaret S. Ho (Editor), R Zorec (Editor), Vladimir Parpura (Editor)

Research output: Book/ReportBookpeer-review

Abstract

This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s.

Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.
Original languageEnglish
Place of PublicationHeidelberg
PublisherSpringer Nature
Number of pages405
ISBN (Electronic)978-981-13-9913-8
ISBN (Print)978-981-13-9912-1
Publication statusPublished - 17 Oct 2019

Publication series

Name Advances in Experimental Medicine and Biology
Volume1175

Keywords

  • Neuroglia
  • Neurodegeneration
  • Alzheimer's Disease
  • a-synucleinopathies
  • Neuropathology

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