Neuropsychological and psychiatric outcomes following coronary surgery or angioplasty: A comparative study

Mark A. Sader, Laurie A. Miller, Diana Caine, Robyn J. McCredie, Melissa J. Corr, Michael Robertson, John D G Watson, David S. Celermajer

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    Background: Medical outcomes following coronary artery bypass grafting (CABG) or percutaneous transluminal coronary angioplasty (PTCA) are similar, but few studies have compared neuropsychological outcomes after these procedures. Methods: A retrospective study compared detailed neurocognitive and psychosocial functioning in 32 patients (CABG, n = 16; PTCA, n = 16) aged 61 ± 6 years, 9-15 months after coronary revascularisation. Subjects were tested for executive functioning, speed of processing/attention and learning/memory, significant psychopathology (General Health Questionnaire, GHQ) and psychosocial functioning (Short Form (SF)-36 health survey). In the rospective study, 55 patients completed GHQ and SF-36 surveys, the day prior to and 6 months following PTCA. Results: There were no significant differences between the CABG and PTCA groups for neuropsychological or psychosocial end-points (P > 0.20). Executive functioning in both groups, however, was worse than for healthy population controls (P <0.01). The PTCA patients were significantly more likely than CABG patients to have psychiatric abnormality (GHQ Score >4; P <0.01). After PTCA, however, there was a significant improvement in the GHQ and SF-36 scores (P <0.05). Conclusions: Although executive function is often impaired after coronary revascularisation, neuropsychological status appears equivalent after CABG or PTCA. Psychiatric pathology is common in patients undergoing PTCA, but improves after this intervention.
    Original languageEnglish
    Pages (from-to)95-101
    Number of pages6
    JournalHeart Lung and Circulation
    Issue number2
    Publication statusPublished - 2002


    • Cognitive
    • Coronary angioplasty
    • Coronary bypass
    • Psychosocial


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