New approaches to the endocrine prevention and treatment of breast cancer.

Sacha Howell; Anthony Howell; Sacha J Howell; D Gareth Evans

doi:10.1007/s00280-003-0645-5

New approaches to the endocrine prevention and treatment of breast cancer.

Sacha Howell, Anthony Howell, Sacha J Howell, D Gareth Evans

Research output: Contribution to journal › Article › peer-review

Abstract

All major endocrine prevention approaches act via the estrogen receptor (ER). A simple hypothesis concerning ER expression and breast cancer risk is outlined. We review breast cancer prevention trials with tamoxifen, raloxifene, aromatase inhibitors, and ovarian suppression. Current and planned endocrine prevention trials in populations of pre- and postmenopausal women at risk of breast cancer are summarized and endocrine therapy after primary surgery and for advanced disease discussed.

Original language	English
Journal	Cancer Chemotherapy and Pharmacology
Volume	52 Suppl 1
DOIs	https://doi.org/10.1007/s00280-003-0645-5
Publication status	Published - Jul 2003

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10.1007/s00280-003-0645-5

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title = "New approaches to the endocrine prevention and treatment of breast cancer.",

abstract = "All major endocrine prevention approaches act via the estrogen receptor (ER). A simple hypothesis concerning ER expression and breast cancer risk is outlined. We review breast cancer prevention trials with tamoxifen, raloxifene, aromatase inhibitors, and ovarian suppression. Current and planned endocrine prevention trials in populations of pre- and postmenopausal women at risk of breast cancer are summarized and endocrine therapy after primary surgery and for advanced disease discussed.",

author = "Sacha Howell and Anthony Howell and Howell, {Sacha J} and Evans, {D Gareth}",

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AB - All major endocrine prevention approaches act via the estrogen receptor (ER). A simple hypothesis concerning ER expression and breast cancer risk is outlined. We review breast cancer prevention trials with tamoxifen, raloxifene, aromatase inhibitors, and ovarian suppression. Current and planned endocrine prevention trials in populations of pre- and postmenopausal women at risk of breast cancer are summarized and endocrine therapy after primary surgery and for advanced disease discussed.

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VL - 52 Suppl 1

JO - Cancer Chemotherapy and Pharmacology

JF - Cancer Chemotherapy and Pharmacology

ER -

New approaches to the endocrine prevention and treatment of breast cancer.

Abstract

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