New diagnostic techniques in staging in the surgical treatment of cutaneous malignant melanoma

D C P Cobben; S Koopal; A T M G Tiebosch; P L Jager; P H Elsinga; Th Wobbes; H J Hoekstra

doi:10.1053/ejso.2002.1319

New diagnostic techniques in staging in the surgical treatment of cutaneous malignant melanoma

D C P Cobben, S Koopal, A T M G Tiebosch, P L Jager, P H Elsinga, Th Wobbes, H J Hoekstra

Division of Cancer Sciences (L5)

Research output: Contribution to journal › Review article › peer-review

Abstract

The emphasis of the research on the surgical treatment of melanoma has been on the resection margins, the role of elective lymph node dissection in high risk patients and the value of adjuvant regional treatment with hyperthermic isolated lymph perfusion with melphalan. Parallel to this research, new diagnostic techniques, such as Positron Emission Tomography and the introduction of the sentinel lymph node biopsy with advanced laboratory methods such as immuno-histochemical markers, and reverse transcriptase polymerase chain reaction, have been developed to facilitate early detection of metastatic melanoma. The role of these new techniques on the staging and surgical treatment of melanoma is discussed in this paper.

Original language	English
Pages (from-to)	692-700
Number of pages	9
Journal	European Journal of Surgical Oncology
Volume	28
Issue number	7
DOIs	https://doi.org/10.1053/ejso.2002.1319
Publication status	Published - Nov 2002

Keywords

Biomarkers, Tumor
Fluorodeoxyglucose F18
Humans
Immunohistochemistry
Melanoma
Neoplasm Staging
Radiopharmaceuticals
Reverse Transcriptase Polymerase Chain Reaction
Sentinel Lymph Node Biopsy
Skin Neoplasms
Tomography, Emission-Computed
Journal Article
Review

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1053/ejso.2002.1319

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title = "New diagnostic techniques in staging in the surgical treatment of cutaneous malignant melanoma",

abstract = "The emphasis of the research on the surgical treatment of melanoma has been on the resection margins, the role of elective lymph node dissection in high risk patients and the value of adjuvant regional treatment with hyperthermic isolated lymph perfusion with melphalan. Parallel to this research, new diagnostic techniques, such as Positron Emission Tomography and the introduction of the sentinel lymph node biopsy with advanced laboratory methods such as immuno-histochemical markers, and reverse transcriptase polymerase chain reaction, have been developed to facilitate early detection of metastatic melanoma. The role of these new techniques on the staging and surgical treatment of melanoma is discussed in this paper.",

keywords = "Biomarkers, Tumor, Fluorodeoxyglucose F18, Humans, Immunohistochemistry, Melanoma, Neoplasm Staging, Radiopharmaceuticals, Reverse Transcriptase Polymerase Chain Reaction, Sentinel Lymph Node Biopsy, Skin Neoplasms, Tomography, Emission-Computed, Journal Article, Review",

author = "Cobben, \{D C P\} and S Koopal and Tiebosch, \{A T M G\} and Jager, \{P L\} and Elsinga, \{P H\} and Th Wobbes and Hoekstra, \{H J\}",

year = "2002",

month = nov,

doi = "10.1053/ejso.2002.1319",

language = "English",

volume = "28",

pages = "692--700",

journal = "European Journal of Surgical Oncology",

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T1 - New diagnostic techniques in staging in the surgical treatment of cutaneous malignant melanoma

AU - Cobben, D C P

AU - Koopal, S

AU - Tiebosch, A T M G

AU - Jager, P L

AU - Elsinga, P H

AU - Wobbes, Th

AU - Hoekstra, H J

PY - 2002/11

Y1 - 2002/11

N2 - The emphasis of the research on the surgical treatment of melanoma has been on the resection margins, the role of elective lymph node dissection in high risk patients and the value of adjuvant regional treatment with hyperthermic isolated lymph perfusion with melphalan. Parallel to this research, new diagnostic techniques, such as Positron Emission Tomography and the introduction of the sentinel lymph node biopsy with advanced laboratory methods such as immuno-histochemical markers, and reverse transcriptase polymerase chain reaction, have been developed to facilitate early detection of metastatic melanoma. The role of these new techniques on the staging and surgical treatment of melanoma is discussed in this paper.

AB - The emphasis of the research on the surgical treatment of melanoma has been on the resection margins, the role of elective lymph node dissection in high risk patients and the value of adjuvant regional treatment with hyperthermic isolated lymph perfusion with melphalan. Parallel to this research, new diagnostic techniques, such as Positron Emission Tomography and the introduction of the sentinel lymph node biopsy with advanced laboratory methods such as immuno-histochemical markers, and reverse transcriptase polymerase chain reaction, have been developed to facilitate early detection of metastatic melanoma. The role of these new techniques on the staging and surgical treatment of melanoma is discussed in this paper.

KW - Biomarkers, Tumor

KW - Fluorodeoxyglucose F18

KW - Humans

KW - Immunohistochemistry

KW - Melanoma

KW - Neoplasm Staging

KW - Radiopharmaceuticals

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Sentinel Lymph Node Biopsy

KW - Skin Neoplasms

KW - Tomography, Emission-Computed

KW - Journal Article

KW - Review

UR - https://www.scopus.com/pages/publications/0036880672

U2 - 10.1053/ejso.2002.1319

DO - 10.1053/ejso.2002.1319

M3 - Review article

C2 - 12431464

SN - 0748-7983

VL - 28

SP - 692

EP - 700

JO - European Journal of Surgical Oncology

JF - European Journal of Surgical Oncology

IS - 7

ER -

New diagnostic techniques in staging in the surgical treatment of cutaneous malignant melanoma

Abstract

Keywords

UN SDGs

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