Non-coding RNAs in Saccharomyces cerevisiae: What is the function?

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    Abstract

    New sequencing technologies and high-resolution microarray analysis have revealed genome-wide pervasive transcription in many eukaryotes, generating a large number of RNAs with no coding capacity. The focus of current debate is whether many of these ncRNAs (non-coding RNAs) are functional, and if so, what their function is. In this review, we describe recent discoveries in the field of ncRNAs in the yeast Saccharomyces cerevisiae. Newly identified ncRNAs in this budding yeast, their functions in gene regulation and possible mechanisms of action are discussed. ©The Authors Journal compilation ©2012 Biochemical Society.
    Original languageEnglish
    Pages (from-to)907-911
    Number of pages4
    JournalBiochemical Society Transactions
    Volume40
    Issue number4
    DOIs
    Publication statusPublished - Aug 2012

    Keywords

    • Histone deacetylase (HDAC)
    • Non-coding RNA
    • Open reading frame
    • Pervasive transcription
    • Saccharomyces cerevisiae

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