Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue

Reza Aghamohammadzadeh; Anthony M. Heagerty

doi:10.3109/07853890.2012.663928

Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue

Reza Aghamohammadzadeh, Anthony M. Heagerty

Research output: Contribution to journal › Article › peer-review

Abstract

The advent of the obesity epidemic has highlighted the need to re-assess more closely the pathophysiology of obesity-related hypertension with the aim of identifying new therapies. In this article, we review the role of the renin-angiotensin-aldosterone system, sympathetic nervous system, and inflammation in relation to the pathophysiology of this condition. We also discuss the potential role of the perivascular adipose tissue in the context of obesity-related hypertension. © 2012 Informa UK, Ltd.

Original language	English
Pages (from-to)	S74-S84
Journal	Annals of Medicine
Volume	44
Issue number	1
DOIs	https://doi.org/10.3109/07853890.2012.663928
Publication status	Published - Jun 2012

Keywords

Adiponectin
bariatric surgery
hypertension
inflammation
obesity
oxidative stress
perivascular adipose tissue
sympathetic nervous system

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3109/07853890.2012.663928

Cite this

@article{8c129236ece84e86bf7776e0acdfe927,

title = "Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue",

abstract = "The advent of the obesity epidemic has highlighted the need to re-assess more closely the pathophysiology of obesity-related hypertension with the aim of identifying new therapies. In this article, we review the role of the renin-angiotensin-aldosterone system, sympathetic nervous system, and inflammation in relation to the pathophysiology of this condition. We also discuss the potential role of the perivascular adipose tissue in the context of obesity-related hypertension. {\textcopyright} 2012 Informa UK, Ltd.",

keywords = "Adiponectin, bariatric surgery, hypertension, inflammation, obesity, oxidative stress, perivascular adipose tissue, sympathetic nervous system",

author = "Reza Aghamohammadzadeh and Heagerty, {Anthony M.}",

year = "2012",

month = jun,

doi = "10.3109/07853890.2012.663928",

language = "English",

volume = "44",

pages = "S74--S84",

journal = "Annals of Medicine",

issn = "0785-3890",

publisher = "Informa Healthcare",

number = "1",

}

TY - JOUR

T1 - Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue

AU - Aghamohammadzadeh, Reza

AU - Heagerty, Anthony M.

PY - 2012/6

Y1 - 2012/6

N2 - The advent of the obesity epidemic has highlighted the need to re-assess more closely the pathophysiology of obesity-related hypertension with the aim of identifying new therapies. In this article, we review the role of the renin-angiotensin-aldosterone system, sympathetic nervous system, and inflammation in relation to the pathophysiology of this condition. We also discuss the potential role of the perivascular adipose tissue in the context of obesity-related hypertension. © 2012 Informa UK, Ltd.

AB - The advent of the obesity epidemic has highlighted the need to re-assess more closely the pathophysiology of obesity-related hypertension with the aim of identifying new therapies. In this article, we review the role of the renin-angiotensin-aldosterone system, sympathetic nervous system, and inflammation in relation to the pathophysiology of this condition. We also discuss the potential role of the perivascular adipose tissue in the context of obesity-related hypertension. © 2012 Informa UK, Ltd.

KW - Adiponectin

KW - bariatric surgery

KW - hypertension

KW - inflammation

KW - obesity

KW - oxidative stress

KW - perivascular adipose tissue

KW - sympathetic nervous system

U2 - 10.3109/07853890.2012.663928

DO - 10.3109/07853890.2012.663928

M3 - Article

SN - 0785-3890

VL - 44

SP - S74-S84

JO - Annals of Medicine

JF - Annals of Medicine

IS - 1

ER -

Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this