Abstract
The stereoselectivity of iodine-promoted glycosylation with mannosyl sulfoxides gives rise to unexpected β-selectivity with less reactive alcohol acceptors. Less reactive accceptors also give better coupling yields. Comparison of iodine with other promoters highlights differences in reaction rates and stereoselectivities indicative of different reaction mechanisms.
| Original language | Undefined |
|---|---|
| Pages (from-to) | 1376-1378 |
| Number of pages | 3 |
| Journal | SYNLETT |
| Issue number | 9 |
| Publication status | Published - 2003 |
Keywords
- Carbohydrates
- Glycosylations
- Iodine
- Stereoselectivity
- Sulfoxides
Research Beacons, Institutes and Platforms
- Manchester Institute of Biotechnology