Occupation exposures and sperm morphology: A case-referent analysis of a multi-centre study

Nicola Cherry, Andy C. Povey, Roseanne McNamee, Harry Moore, Helen Baillie, Julie Ann Clyma, Martin Dippnall, Allan A. Pacey

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective: We examined occupational exposures and sperm morphology to establish whether exposures implicated differed from those affecting motile sperm concentration. Methods: Computer aided sperm morphometric assessment was undertaken on morphology slides obtained as part of a multi-centre study in 1999-2002 of occupational factors in male infertility. Men attending 14 fertility clinics across the UK were recruited and gave a semen sample. Before results of the semen analysis were known, the men completed detailed questionnaires about their employment and lifestyle. Occupational exposures were assessed by occupational hygienists. Data were analysed using an unmatched case-referent design, allowing for clustering and for confounders. Three case definitions were used: poor morphology (normal morphology
    Original languageEnglish
    Pages (from-to)598-604
    Number of pages6
    JournalOccupational and Environmental Medicine
    Volume71
    Issue number9
    DOIs
    Publication statusPublished - 2014

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