Occupational asthma caused by an epoxy amine hardener

O. Vandenplas*, C. Rifflart, G. Evrard, J. Thimpont, M. Seed, R. Agius

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a 43-year-old epoxy floor layer who developed work-related asthma while exposed to an epoxy hardener based on isophorone diamine (IPDA). Challenge exposures to the curing of the epoxy resin system and subsequently to the polyfunctional amine hardener containing IPDA both elicited delayed asthmatic reactions. This report further indicates that exposure to epoxy hardeners containing polyfunctional amines should be considered as a potential cause of occupational asthma. Appropriate work hygiene measures should be implemented to minimize airborne exposure to these volatile compounds.

Original languageEnglish
Article numberkqx151
Pages (from-to)22-724
Number of pages703
JournalOccupational Medicine
Volume67
Issue number9
DOIs
Publication statusPublished - 12 Oct 2017

Keywords

  • Amines
  • Asthma
  • Bronchoprovocation tests
  • Occupational diseases

Research Beacons, Institutes and Platforms

  • Manchester Institute for Collaborative Research on Ageing

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