Ocular Manifestations of Scleroderma

Rajen Tailor, Abha Gupta, Ariane Herrick, Jeffrey Kwartz

    Research output: Contribution to journalArticlepeer-review


    Systemic sclerosis is a chronic multi-system disorder predominantly affecting the skin, musculoskeletal, gastrointestinal, pulmonary, and renal systems. Although the exact etiology is unknown, recent evidence suggests that immune activation play a pivotal role in the pathogenesis. Ocular involvement in systemic sclerosis has been documented; however, due to the rare nature of the disease, most papers have been single case reports or small case series. This review paper aims to consolidate the findings of previous papers with a view to providing a comprehensive review of the ocular manifestations of systemic sclerosis. © 2009 Elsevier Inc. All rights reserved.
    Original languageEnglish
    Pages (from-to)292-304
    Number of pages12
    JournalSurvey of ophthalmology
    Issue number2
    Publication statusPublished - Mar 2009


    • pathogenesis
    • scleroderma
    • systemic sclerosis


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