Omega-3 fatty acids and skin

S Pilkington, Lesley Rhodes

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Using nutrients such as omega-3 polyunsaturated fatty acids (n-3 PUFAs) for the promotion of skin health and treatment of skin disorders is a novel concept. These bioactive fatty acids have a high safety profile and could potentially be used as an adjuvant or alternative to traditional therapy. Evidence exists to suggest that n-3 PUFA exert their protective effects in biological tissues via a range of mechanisms, from alteration of receptor mediated signaling at cellular membranes to eicosanoid signaling and transcriptional activation. A more detailed examination of the activities of n-3 PUFA in the skin is required to enable dissection of the molecular actions of these fats. This could lead to the development of targeted natural treatments in addition to enhancing our understanding of how diet impacts upon skin function.

Original languageEnglish
Title of host publicationNutrition for Healthy Skin: Strategies for Clinical and Cosmetic Practice
Subtitle of host publicationStrategies for Clinical and Cosmetic Practice
EditorsJean Krutmann, Philippe Humbert
PublisherSpringer Nature
Number of pages17
ISBN (Print)9783642122637
Publication statusPublished - 1 Dec 2011


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