On-off transport through a thermoresponsive hydrogel composite membrane

S. K. Li, A. D'Emanuele

    Research output: Contribution to journalArticlepeer-review


    A novel thermoresponsive composite membrane is described through which the permeation of molecules is dependent on the temperature of the milieu. The thermoresponsive composite membranes utilise a thermosensitive crosslinked polymeric hydrogel, which possesses a volume phase transition temperature (VPTT). The hydrogel was polymerised in situ within the pores of a sintered glass filter, through which significant permeation of molecules only occurred at temperatures above the VPTT of the hydrogel. It was found that the permeation of molecules through the thermoresponsive composite membranes could be modulated by changing the environmental temperature. © 2001 Elsevier Science B.V.
    Original languageEnglish
    Pages (from-to)55-67
    Number of pages12
    JournalJournal of Controlled Release
    Issue number1-2
    Publication statusPublished - 10 Jul 2001


    • Cryo-scanning electron microscopy
    • N-isopropylacrylamide
    • Temperature-modulated drug delivery system
    • Thermoresponsive hydrogel
    • Thermoresponsive membrane


    Dive into the research topics of 'On-off transport through a thermoresponsive hydrogel composite membrane'. Together they form a unique fingerprint.

    Cite this