Abstract
Objectives: The study aimed to explore patients’ experiences of experimental cancer medicine (ECM) clinical trials.
Design: The study’s design was qualitative. Two focus groups with patients were undertaken followed by semi structured interviews, to explore patients’ experiences of ECM clinical trials. Interviews and focus groups were audio recorded and transcribed verbatim. Data were analysed using thematic analysis.
Setting: A regional cancer centre (tertiary care) in North-West England.
Participants: Twelve patients (aged 52–79) participated in one of the two focus groups and 22 patients (aged 42–83) participated in interviews.
Primary outcome measure: Patients’ experiences of an ECM trial.
Results: Four main themes were identified from the analysis: decision making, information needs, the experience of trial participation and impact of trial participation. Subthemes are presented in the manuscript.
Conclusion: To make fully informed decisions about trial participation, patients required the simplification of trial information and wanted more information about side effects, their response to trial treatment and the overall trial progress throughout the trial. Patients highlighted the need for improvement for the support provided to their family and friends.
Design: The study’s design was qualitative. Two focus groups with patients were undertaken followed by semi structured interviews, to explore patients’ experiences of ECM clinical trials. Interviews and focus groups were audio recorded and transcribed verbatim. Data were analysed using thematic analysis.
Setting: A regional cancer centre (tertiary care) in North-West England.
Participants: Twelve patients (aged 52–79) participated in one of the two focus groups and 22 patients (aged 42–83) participated in interviews.
Primary outcome measure: Patients’ experiences of an ECM trial.
Results: Four main themes were identified from the analysis: decision making, information needs, the experience of trial participation and impact of trial participation. Subthemes are presented in the manuscript.
Conclusion: To make fully informed decisions about trial participation, patients required the simplification of trial information and wanted more information about side effects, their response to trial treatment and the overall trial progress throughout the trial. Patients highlighted the need for improvement for the support provided to their family and friends.
| Original language | English |
|---|---|
| Article number | 047813 |
| Journal | BMJ Open |
| Volume | 11 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 5 Oct 2021 |
Keywords
- Biomedical Research
- Focus Groups
- Humans
- Medical Oncology
- Neoplasms/therapy
- Qualitative Research
- adult oncology
- clinical trials
- qualitative research
