Online monitoring and flow regime identification of fluidised bed drying and granulation processes

Haigang Wang; Wuqiang Yang; Ian Proctor; Julian Taylor; Alex Marr; Trevor Page

doi:10.1109/IST.2009.5071643

Online monitoring and flow regime identification of fluidised bed drying and granulation processes

Haigang Wang, Wuqiang Yang, Ian Proctor, Julian Taylor, Alex Marr, Trevor Page

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

Abstract

Fluidised beds are widely used in the pharmaceutical industry for granulation, drying and coating. The product quality strongly depends on the operation parameters and process conditions, e.g. inlet airflow rate, temperature and spraying flow rate. For granulation and drying processes, the flow conditions can change dramatically due to different moisture level, because of the change in physical characteristics of particles, including viscosity, density and diameter. Also, the flow regime of a fluidised bed would change with the diameter and density of particles. Due to high moisture content, particles could agglomerate and stick up to the wall and distributor plate, resulting in a fault process. Therefore, it is necessary to monitor a drying or granulation process, identify their flow regime and control the processes according to the particle properties. This paper describes an application of electrical capacitance tomography (ECT) to monitor the process conditions and for diagnosis of fault with a semi-industrial scale pharmaceutical fluidised bed. Preliminary test results with granulation and drying processes are given. Future work on fluidised bed control based on the information provided by ECT will be discussed. © 2009 IEEE.

Original language	English
Title of host publication	2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings\|IEEE Int. Workshop Imaging Syst. Tech., IST - Proc.
Place of Publication	USA
Publisher	IEEE
Pages	253-257
Number of pages	4
ISBN (Print)	9781424434831
DOIs	https://doi.org/10.1109/IST.2009.5071643
Publication status	Published - 2009
Event	2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Hong Kong Duration: 1 Jul 2009 → …

Conference

Conference	2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009
City	Hong Kong
Period	1/07/09 → …

Keywords

Drying
Electrical capacitance tomography
Fluidised bed
Granulation

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10.1109/IST.2009.5071643

Cite this

Wang, H., Yang, W., Proctor, I., Taylor, J., Marr, A., & Page, T. (2009). Online monitoring and flow regime identification of fluidised bed drying and granulation processes. In 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings|IEEE Int. Workshop Imaging Syst. Tech., IST - Proc. (pp. 253-257). IEEE. https://doi.org/10.1109/IST.2009.5071643

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title = "Online monitoring and flow regime identification of fluidised bed drying and granulation processes",

abstract = "Fluidised beds are widely used in the pharmaceutical industry for granulation, drying and coating. The product quality strongly depends on the operation parameters and process conditions, e.g. inlet airflow rate, temperature and spraying flow rate. For granulation and drying processes, the flow conditions can change dramatically due to different moisture level, because of the change in physical characteristics of particles, including viscosity, density and diameter. Also, the flow regime of a fluidised bed would change with the diameter and density of particles. Due to high moisture content, particles could agglomerate and stick up to the wall and distributor plate, resulting in a fault process. Therefore, it is necessary to monitor a drying or granulation process, identify their flow regime and control the processes according to the particle properties. This paper describes an application of electrical capacitance tomography (ECT) to monitor the process conditions and for diagnosis of fault with a semi-industrial scale pharmaceutical fluidised bed. Preliminary test results with granulation and drying processes are given. Future work on fluidised bed control based on the information provided by ECT will be discussed. {\textcopyright} 2009 IEEE.",

keywords = "Drying, Electrical capacitance tomography, Fluidised bed, Granulation",

author = "Haigang Wang and Wuqiang Yang and Ian Proctor and Julian Taylor and Alex Marr and Trevor Page",

year = "2009",

doi = "10.1109/IST.2009.5071643",

language = "English",

isbn = "9781424434831",

pages = "253--257",

booktitle = "2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings|IEEE Int. Workshop Imaging Syst. Tech., IST - Proc.",

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Wang, H, Yang, W, Proctor, I, Taylor, J, Marr, A & Page, T 2009, Online monitoring and flow regime identification of fluidised bed drying and granulation processes. in 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings|IEEE Int. Workshop Imaging Syst. Tech., IST - Proc.. IEEE, USA, pp. 253-257, 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009, Hong Kong, 1/07/09. https://doi.org/10.1109/IST.2009.5071643

Online monitoring and flow regime identification of fluidised bed drying and granulation processes. / Wang, Haigang; Yang, Wuqiang; Proctor, Ian et al.
2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings|IEEE Int. Workshop Imaging Syst. Tech., IST - Proc.. USA: IEEE, 2009. p. 253-257.

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

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T1 - Online monitoring and flow regime identification of fluidised bed drying and granulation processes

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AU - Yang, Wuqiang

AU - Proctor, Ian

AU - Taylor, Julian

AU - Marr, Alex

AU - Page, Trevor

PY - 2009

Y1 - 2009

N2 - Fluidised beds are widely used in the pharmaceutical industry for granulation, drying and coating. The product quality strongly depends on the operation parameters and process conditions, e.g. inlet airflow rate, temperature and spraying flow rate. For granulation and drying processes, the flow conditions can change dramatically due to different moisture level, because of the change in physical characteristics of particles, including viscosity, density and diameter. Also, the flow regime of a fluidised bed would change with the diameter and density of particles. Due to high moisture content, particles could agglomerate and stick up to the wall and distributor plate, resulting in a fault process. Therefore, it is necessary to monitor a drying or granulation process, identify their flow regime and control the processes according to the particle properties. This paper describes an application of electrical capacitance tomography (ECT) to monitor the process conditions and for diagnosis of fault with a semi-industrial scale pharmaceutical fluidised bed. Preliminary test results with granulation and drying processes are given. Future work on fluidised bed control based on the information provided by ECT will be discussed. © 2009 IEEE.

AB - Fluidised beds are widely used in the pharmaceutical industry for granulation, drying and coating. The product quality strongly depends on the operation parameters and process conditions, e.g. inlet airflow rate, temperature and spraying flow rate. For granulation and drying processes, the flow conditions can change dramatically due to different moisture level, because of the change in physical characteristics of particles, including viscosity, density and diameter. Also, the flow regime of a fluidised bed would change with the diameter and density of particles. Due to high moisture content, particles could agglomerate and stick up to the wall and distributor plate, resulting in a fault process. Therefore, it is necessary to monitor a drying or granulation process, identify their flow regime and control the processes according to the particle properties. This paper describes an application of electrical capacitance tomography (ECT) to monitor the process conditions and for diagnosis of fault with a semi-industrial scale pharmaceutical fluidised bed. Preliminary test results with granulation and drying processes are given. Future work on fluidised bed control based on the information provided by ECT will be discussed. © 2009 IEEE.

KW - Drying

KW - Electrical capacitance tomography

KW - Fluidised bed

KW - Granulation

U2 - 10.1109/IST.2009.5071643

DO - 10.1109/IST.2009.5071643

M3 - Conference contribution

SN - 9781424434831

SP - 253

EP - 257

BT - 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings|IEEE Int. Workshop Imaging Syst. Tech., IST - Proc.

PB - IEEE

CY - USA

T2 - 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009

Y2 - 1 July 2009

ER -

Online monitoring and flow regime identification of fluidised bed drying and granulation processes

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