Opsonizing activity of C-reactive protein in phagocytosis of Aspergillus fumigatus conidia by human neutrophils

M. D. Richardson; G. S. Shankland; C. A. Gray

Opsonizing activity of C-reactive protein in phagocytosis of Aspergillus fumigatus conidia by human neutrophils

M. D. Richardson, G. S. Shankland, C. A. Gray

Research output: Contribution to journal › Article › peer-review

Abstract

In complement-free neutrophil monolayer assays pathological levels of C-reactive protein (CRP) were found to promote greater phagocytosis of metabolically-active conidia of Aspergillus fumigatus than dormant spores. This suggests that metabolically-active conidia bind CRP which facilitates in vitro phagocytosis by human neutrophils.

Original language	English
Pages (from-to)	141-143
Number of pages	2
Journal	MYCOSES
Volume	34
Issue number	3-4
Publication status	Published - 1991

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@article{a9501ccbcdba4842ada9093941e6f776,

title = "Opsonizing activity of C-reactive protein in phagocytosis of Aspergillus fumigatus conidia by human neutrophils",

abstract = "In complement-free neutrophil monolayer assays pathological levels of C-reactive protein (CRP) were found to promote greater phagocytosis of metabolically-active conidia of Aspergillus fumigatus than dormant spores. This suggests that metabolically-active conidia bind CRP which facilitates in vitro phagocytosis by human neutrophils.",

author = "Richardson, {M. D.} and Shankland, {G. S.} and Gray, {C. A.}",

year = "1991",

language = "English",

volume = "34",

pages = "141--143",

journal = "MYCOSES",

issn = "1439-0507",

publisher = "John Wiley & Sons Ltd",

number = "3-4",

}

TY - JOUR

T1 - Opsonizing activity of C-reactive protein in phagocytosis of Aspergillus fumigatus conidia by human neutrophils

AU - Richardson, M. D.

AU - Shankland, G. S.

AU - Gray, C. A.

PY - 1991

Y1 - 1991

N2 - In complement-free neutrophil monolayer assays pathological levels of C-reactive protein (CRP) were found to promote greater phagocytosis of metabolically-active conidia of Aspergillus fumigatus than dormant spores. This suggests that metabolically-active conidia bind CRP which facilitates in vitro phagocytosis by human neutrophils.

AB - In complement-free neutrophil monolayer assays pathological levels of C-reactive protein (CRP) were found to promote greater phagocytosis of metabolically-active conidia of Aspergillus fumigatus than dormant spores. This suggests that metabolically-active conidia bind CRP which facilitates in vitro phagocytosis by human neutrophils.

M3 - Article

C2 - 1749393

SN - 1439-0507

VL - 34

SP - 141

EP - 143

JO - MYCOSES

JF - MYCOSES

IS - 3-4

ER -

Opsonizing activity of C-reactive protein in phagocytosis of Aspergillus fumigatus conidia by human neutrophils

Abstract

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