Optimising the cut-off of the Bordier Aspergillus IgG ELISA for the diagnosis of chronic pulmonary aspergillosis

Bayu A.P. Wilopo, Elizabeth Hunter, Malcolm Richardson, D W Denning

Research output: Contribution to journalArticlepeer-review

Abstract

Aspergillus IgG detection is an essential tool in the diagnosis and treatment of chronic pulmonary aspergillosis (CPA), and is often positive in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis. The Bordier ELISA had an 83.3% sensitivity (identical to ImmunoCap at a cut-off of 40mgA/L) and 97.3% specificity using a cut-off of 0.9 and a diagnostic accuracy of 90.9%.
Original languageEnglish
JournalJournal of Microbiological Methods
Publication statusAccepted/In press - 23 Jul 2020

Keywords

  • Aspergillus fumigatus
  • bordier
  • chronic pulmonary aspergillosis
  • diagnosis
  • ELISA

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