Ornithine decarboxylase inhibition and the uterotrophic response to oestrogen in rats

K. Marshall; Judith Senior

Ornithine decarboxylase inhibition and the uterotrophic response to oestrogen in rats

Pharmacy

Research output: Contribution to journal › Article › peer-review

Abstract

Pretreatment of mature ovariectomized rats with DL-5α-difluoromethylornithine (DFMO) inhibits the 6-h uterine blood flow response to oestradiol and also depresses the stimulatory effect of oestradiol on wet and dry uterine weight. Results from this study indicate that polyamine synthesis is implicated in the uterine response to oestrogen.

Original language	English
Pages (from-to)	587-601
Number of pages	15
Journal	Journal of Reproduction and Fertility
Volume	76
Issue number	2
Publication status	Published - 1986

Keywords

Animal
Body Water
Contraceptives, Postcoital, Synthetic
EflornithineEstradiol
Female
Organ Weight
Ornithine
Ornithine Decarboxylase
Ovariectomy
Polyamines
Rats
Regional Blood Flow
Support, Non-U.S. Gov't
Uterus

Cite this

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title = "Ornithine decarboxylase inhibition and the uterotrophic response to oestrogen in rats",

abstract = "Pretreatment of mature ovariectomized rats with DL-5α-difluoromethylornithine (DFMO) inhibits the 6-h uterine blood flow response to oestradiol and also depresses the stimulatory effect of oestradiol on wet and dry uterine weight. Results from this study indicate that polyamine synthesis is implicated in the uterine response to oestrogen.",

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author = "K. Marshall and Judith Senior",

year = "1986",

language = "English",

volume = "76",

pages = "587--601",

journal = " Journal of Reproduction and Fertility ",

issn = "0022-4251",

publisher = "Society for Reproduction and Fertility",

number = "2",

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T1 - Ornithine decarboxylase inhibition and the uterotrophic response to oestrogen in rats

AU - Marshall, K.

AU - Senior, Judith

PY - 1986

Y1 - 1986

N2 - Pretreatment of mature ovariectomized rats with DL-5α-difluoromethylornithine (DFMO) inhibits the 6-h uterine blood flow response to oestradiol and also depresses the stimulatory effect of oestradiol on wet and dry uterine weight. Results from this study indicate that polyamine synthesis is implicated in the uterine response to oestrogen.

AB - Pretreatment of mature ovariectomized rats with DL-5α-difluoromethylornithine (DFMO) inhibits the 6-h uterine blood flow response to oestradiol and also depresses the stimulatory effect of oestradiol on wet and dry uterine weight. Results from this study indicate that polyamine synthesis is implicated in the uterine response to oestrogen.

KW - Animal

KW - Body Water

KW - Contraceptives, Postcoital, Synthetic

KW - EflornithineEstradiol

KW - Female

KW - Organ Weight

KW - Ornithine

KW - Ornithine Decarboxylase

KW - Ovariectomy

KW - Polyamines

KW - Rats

KW - Regional Blood Flow

KW - Support, Non-U.S. Gov't

KW - Uterus

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M3 - Article

SN - 0022-4251

VL - 76

SP - 587

EP - 601

JO - Journal of Reproduction and Fertility

JF - Journal of Reproduction and Fertility

IS - 2

ER -

Ornithine decarboxylase inhibition and the uterotrophic response to oestrogen in rats

Abstract

Keywords

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