Orofacial dyskinesia, frontal lobe dysfunction, and coping in older people with psychosis

Katherine Berry, Richard Drake, Catherine Stewart, Lisa Marie Aitkin, Jane Byrne, Christine Barrowclough, Nitin Purandare

Research output: Contribution to journalArticlepeer-review


OBJECTIVE:: To investigate whether orofacial tardive dyskinesia (OTD) is associated with frontal lobe dysfunction and whether either are related to the coping abilities independent of psychiatric symptoms in older people with psychotic disorders. METHODS:: A total of 52 patients, aged over 65 years or over, who satisfied International Classification of Diseases, Tenth Revision criteria for psychotic disorders (F20ĝ€"F29) were recruited into the study. OTD was measured using the Abnormal Involuntary Movements Scale and Waddington et als (1993) criteria. Neuropsychological measures were specifically selected to assess different aspects of frontal function and coping was measured using a semistructured interview. Psychiatric symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS). RESULTS:: Patients with OTD showed more severe global cognitive impairment compared to patients without OTD. Group differences on measures of frontal lobe dysfunction were not maintained following adjustment for global cognitive impairment. Patients with OTD did not differ from patients without OTD on coping measures. Scores on the general psychopathology subscale of the PANSS, which includes symptoms associated with depression and anxiety, consistently predicted patients negative perceptions of stressors and appraisals of coping, but cognitive impairment did not predict coping independent of symptoms. CONCLUSION:: The association between coping and general psychopathology in older patients with psychosis warrants further investigation as both variables may be amenable to psychological interventions. © 2007 American Association for Geriatric Psychiatry.
Original languageEnglish
Pages (from-to)800-806
Number of pages6
JournalAmerican Journal of Geriatric Psychiatry
Issue number9
Publication statusPublished - Sep 2007


  • Coping
  • Frontal lobe
  • Old age
  • Orofacial dyskinesia
  • Psychosis


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