Outcomes for Supratentorial Primitive Neuroectodermal Tumours (SPNET) diagnosed in the North West region of the UK during 1954-2008

R Alston, C Yap, R Jassal, D Ormandy, N Addo, O Rominiyi, JM Birch, HR Gattamaneni, EJ Estlin, I Kamaly-Asl

    Research output: Contribution to conferencePoster

    Abstract

    Background: Historically, SPNETs account for 2.5% of childhood CNS tumours and have a poor prognosis.Aim: This project aims to identify factors and trends in survival among children with SPNETs in the North-west region between 1954-2008.Method: Patients who had been diagnosed with SPNETs in the North West Region between years 1954-2008 were extracted from the database in the North West Children’s Tumour Registry. Data relating to presentation, management and survival for these patients were analysed.Results: There were 18 male and 12 female SPNET patients identified (2.1% of the registry total). Median age at diagnosis was 4 years 11 months. By univariate analysis, both chemotherapy (p=0.008) and radiotherapy (p=0.004) improved survival. Median survival improved with time from 6 months to 8 years 4 months between the first and second halves of the cohort (p
    Original languageEnglish
    Publication statusPublished - 2012
    Event40th Annual meeting of the International Society for Paediatric Neurosurgery - Sydney, Ausralia
    Duration: 9 Sept 201212 Sept 2012

    Conference

    Conference40th Annual meeting of the International Society for Paediatric Neurosurgery
    CitySydney, Ausralia
    Period9/09/1212/09/12

    Keywords

    • CNS tumours
    • Children
    • North-West of United Kingdom

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