Outcomes in patients with acute and stable coronary syndromes; insights from the prospective NOBORI-2 study

Mamas Mamas; Farzin Fath-Ordoubadi; Erik Spaepen; Magdi El-Omar; Douglas G. Fraser; Muhammad A. Khan; Ludwig Neyses; Gian B. Danzi; Ariel Roguin; Dragica Paunovic; Mamas A. Mamas

doi:10.1371/journal.pone.0088577

Outcomes in patients with acute and stable coronary syndromes; insights from the prospective NOBORI-2 study

Mamas Mamas, Farzin Fath-Ordoubadi, Erik Spaepen, Magdi El-Omar, Douglas G. Fraser, Muhammad A. Khan, Ludwig Neyses, Gian B. Danzi, Ariel Roguin, Dragica Paunovic, Mamas A. Mamas

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Abstract

Background: Contemporary data remains limited regarding mortality and major adverse cardiac events (MACE) outcomes in patients undergoing PCI for different manifestations of coronary artery disease. Objectives: We evaluated mortality and MACE outcomes in patients treated with PCI for STEMI (ST-elevation myocardial infarction), NSTEMI (non ST-elevation myocardial infarction) and stable angina through analysis of data derived from the Nobori-2 study. Methods: Clinical endpoints were cardiac mortality and MACE (a composite of cardiac death, myocardial infarction and target vessel revascularization). Results: 1909 patients who underwent PCI were studied; 1332 with stable angina, 248 with STEMI and 329 with NSTEMI. Age-adjusted Charlson co-morbidity index was greatest in the NSTEMI cohort (3.78±1.91) and lowest in the stable angina cohort (3.00±1.69); P

Original language	English
Article number	e88577
Journal	PLoS ONE
Volume	9
Issue number	2
DOIs	https://doi.org/10.1371/journal.pone.0088577
Publication status	Published - 14 Feb 2014

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title = "Outcomes in patients with acute and stable coronary syndromes; insights from the prospective NOBORI-2 study",

abstract = "Background: Contemporary data remains limited regarding mortality and major adverse cardiac events (MACE) outcomes in patients undergoing PCI for different manifestations of coronary artery disease. Objectives: We evaluated mortality and MACE outcomes in patients treated with PCI for STEMI (ST-elevation myocardial infarction), NSTEMI (non ST-elevation myocardial infarction) and stable angina through analysis of data derived from the Nobori-2 study. Methods: Clinical endpoints were cardiac mortality and MACE (a composite of cardiac death, myocardial infarction and target vessel revascularization). Results: 1909 patients who underwent PCI were studied; 1332 with stable angina, 248 with STEMI and 329 with NSTEMI. Age-adjusted Charlson co-morbidity index was greatest in the NSTEMI cohort (3.78±1.91) and lowest in the stable angina cohort (3.00±1.69); P",

author = "Mamas Mamas and Farzin Fath-Ordoubadi and Erik Spaepen and Magdi El-Omar and Fraser, {Douglas G.} and Khan, {Muhammad A.} and Ludwig Neyses and Danzi, {Gian B.} and Ariel Roguin and Dragica Paunovic and Mamas, {Mamas A.}",

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doi = "10.1371/journal.pone.0088577",

language = "English",

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T1 - Outcomes in patients with acute and stable coronary syndromes; insights from the prospective NOBORI-2 study

AU - Mamas, Mamas

AU - Fath-Ordoubadi, Farzin

AU - Spaepen, Erik

AU - El-Omar, Magdi

AU - Fraser, Douglas G.

AU - Khan, Muhammad A.

AU - Neyses, Ludwig

AU - Danzi, Gian B.

AU - Roguin, Ariel

AU - Paunovic, Dragica

AU - Mamas, Mamas A.

PY - 2014/2/14

Y1 - 2014/2/14

N2 - Background: Contemporary data remains limited regarding mortality and major adverse cardiac events (MACE) outcomes in patients undergoing PCI for different manifestations of coronary artery disease. Objectives: We evaluated mortality and MACE outcomes in patients treated with PCI for STEMI (ST-elevation myocardial infarction), NSTEMI (non ST-elevation myocardial infarction) and stable angina through analysis of data derived from the Nobori-2 study. Methods: Clinical endpoints were cardiac mortality and MACE (a composite of cardiac death, myocardial infarction and target vessel revascularization). Results: 1909 patients who underwent PCI were studied; 1332 with stable angina, 248 with STEMI and 329 with NSTEMI. Age-adjusted Charlson co-morbidity index was greatest in the NSTEMI cohort (3.78±1.91) and lowest in the stable angina cohort (3.00±1.69); P

AB - Background: Contemporary data remains limited regarding mortality and major adverse cardiac events (MACE) outcomes in patients undergoing PCI for different manifestations of coronary artery disease. Objectives: We evaluated mortality and MACE outcomes in patients treated with PCI for STEMI (ST-elevation myocardial infarction), NSTEMI (non ST-elevation myocardial infarction) and stable angina through analysis of data derived from the Nobori-2 study. Methods: Clinical endpoints were cardiac mortality and MACE (a composite of cardiac death, myocardial infarction and target vessel revascularization). Results: 1909 patients who underwent PCI were studied; 1332 with stable angina, 248 with STEMI and 329 with NSTEMI. Age-adjusted Charlson co-morbidity index was greatest in the NSTEMI cohort (3.78±1.91) and lowest in the stable angina cohort (3.00±1.69); P

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DO - 10.1371/journal.pone.0088577

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VL - 9

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Outcomes in patients with acute and stable coronary syndromes; insights from the prospective NOBORI-2 study

Abstract

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