Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast

Nigel Bundred, C. Correa, P. McGale, C. Taylor, Y. Wang, M. Clarke, C. Davies, R. Peto, N. Bijker, L. Solin, S. Darby

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2% (SE 1.6%, 12.9% vs 28.1% 2 P
    Original languageEnglish
    Pages (from-to)162-177
    Number of pages15
    JournalJournal of the National Cancer Institute - Monographs
    Issue number41
    DOIs
    Publication statusPublished - Oct 2010

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