Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast

Nigel Bundred; C. Correa; P. McGale; C. Taylor; Y. Wang; M. Clarke; C. Davies; R. Peto; N. Bijker; L. Solin; S. Darby

doi:10.1093/jncimonographs/lgq039

Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast

Nigel Bundred
, C. Correa
, P. McGale
, C. Taylor
, Y. Wang
, M. Clarke
, C. Davies
, R. Peto
, N. Bijker
, L. Solin
, S. Darby

Research output: Contribution to journal › Article › peer-review

Abstract

Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2% (SE 1.6%, 12.9% vs 28.1% 2 P

Original language	English
Pages (from-to)	162-177
Number of pages	15
Journal	Journal of the National Cancer Institute - Monographs
Issue number	41
DOIs	https://doi.org/10.1093/jncimonographs/lgq039
Publication status	Published - Oct 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1093/jncimonographs/lgq039

Cite this

@article{e0dda2e80540422383d55b4f6315a1ff,

title = "Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast",

abstract = "Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2\% (SE 1.6\%, 12.9\% vs 28.1\% 2 P",

author = "Nigel Bundred and C. Correa and P. McGale and C. Taylor and Y. Wang and M. Clarke and C. Davies and R. Peto and N. Bijker and L. Solin and S. Darby",

year = "2010",

month = oct,

doi = "10.1093/jncimonographs/lgq039",

language = "English",

pages = "162--177",

journal = "Journal of the National Cancer Institute - Monographs",

issn = "1052-6773",

publisher = "Oxford University Press",

number = "41",

}

TY - JOUR

T1 - Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast

AU - Bundred, Nigel

AU - Correa, C.

AU - McGale, P.

AU - Taylor, C.

AU - Wang, Y.

AU - Clarke, M.

AU - Davies, C.

AU - Peto, R.

AU - Bijker, N.

AU - Solin, L.

AU - Darby, S.

PY - 2010/10

Y1 - 2010/10

N2 - Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2% (SE 1.6%, 12.9% vs 28.1% 2 P

AB - Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2% (SE 1.6%, 12.9% vs 28.1% 2 P

U2 - 10.1093/jncimonographs/lgq039

DO - 10.1093/jncimonographs/lgq039

M3 - Article

SN - 1052-6773

SP - 162

EP - 177

JO - Journal of the National Cancer Institute - Monographs

JF - Journal of the National Cancer Institute - Monographs

IS - 41

ER -

Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this