Overview on theoretical studies discriminating the two-oxidant versus two-state-reactivity models for substrate monoxygenation by cytochrome p450 enzymes

Chemistry

• Reactivity 100%
• Cytochrome P450 100%
• Heme 50%
• Spin State 33%
• Hydroxylation 16%
• Hydroxyl Group 16%
• Procedure 16%
• Alcohol 16%
• Chemical Reaction Product 16%
• Hydrogen Atom 16%
• Density Functional Theory Study 16%
• Chemical Reaction 16%
• Product Distribution 16%
• Radical Cation 16%
• Kinetic Isotope Effect 16%
• Epoxidation 16%
• Enzymatic Reaction 16%
• Chemistry 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Oxidizing Agent 100%
• Cytochrome P450 100%
• Enzyme 100%
• Heme 50%
• Experimental Study 33%
• Hydroxyl Group 16%
• Ethanol 16%
• Iron 16%
• Cations 16%
• Isotope 16%
• Hydrogen 16%

Biochemistry, Genetics and Molecular Biology

• Cytochrome P450 100%
• Species 50%
• Acceleration 33%
• Iron 33%
• Epoxidation 16%
• Lysozyme 16%
• Kinetic Isotope Effect 16%
• Atom 16%
• Sulfoxidation 16%
• Precursor 16%
• Hydroxylation 16%
• Density 16%
• Comprehension 16%